STUDY OF OUTCOME IN CONGENITAL DIAPHRAGMATIC HERNIA IN NEONATES

Mohamed Zaheer KB, Ravi K

Abstract


Aim: The aim of this study was to analyze the neonates treated for congenital diaphragmatic hernia and to study the prognostic factors affecting the outcome.

Settings and Design:  The study was a retrospective study of CDH admitted in our Institute from January 2014 to Dec 2019.

Materials and Methods: All cases of CDH undergoing surgery in our hospital were included. Babies who had eventration  of the diaphragm were not included

Results :  One hundred and forty cases (68% Males, 54 % inborn, and 75% > 37 weeks) were studied. Mean Birth weight was 2855 ± 570.60 g and mean gestational age was 37.55 ± 1.75 weeks.

The survival rate was 61%. Factors adversely affecting outcome were herniation of liver or stomach (p<0.05), low APGAR score at 5 min (<5),  presence of moderate to severe PPHN (p<0.001) , presence of shock (p<0.003),low partial pressure of oxygen, high alveolar – arterial oxygen gradient and high oxygenation index.

Conclusion: Morbidity rates were higher in newborns with low Apgar score, moderate to severe PPHN, need for hi gher ventilatory settings in our institution. Antenatal diagnosis failed  to influence the outcome.

Keywords


Congenital diaphragmatic hernia, neonatal, prognostic factors.

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