MULTIPLE-DRUG RESISTANCE IN GRAM NEGATIVE BACTERIA ISOLATED FROM UPPER RESPIRATORY TRACT.

Dr N. V. Naik

Abstract


There is a high prevalence of multiple drug-resistant (MDR) strains which has resulted due to the over use of antibiotics today. Antimicrobial resistance in nosocomial infections is increasing with both morbidity and mortality greater when drug resistant organisms cause the infection. Nosocomial infections are typically exogenous, the source being any part of the hospital ecosystem. Bacteria causing these infections are opportunistic and can cause disease in hospitalized patients whose immune mechanisms are impaired. Many antibiotics can no longer be used for the treatment of infections caused by such organisms. MDR infections are often significantly harder and more expensive to treat, hence represent a growing public health threat and challenge in medicine. Widespread antibiotic resistance and longer survival in the hospital environment has enhanced opportunities for transmission of such pathogens in patients.

Keywords


Multiple drug resistance, nosocomial infections

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