EOSINOPHIL COUNT AND ITS IMPACT ON GENERAL ANESTHESIA

Nari M Lyngdoh, Rajani Thabah, Chhandasi Naskar, Sunny Aggarwal, Melam Surong

Abstract


The association between absolute eosinophil count and perioperative respiratory dysfunction is a risk factor for the development of adverse respiratory events. Important diseases associated with high eosinophil count are asthma, drug allergies, skin diseases, parasitic infections, acute lymphoblstic leukemia, Hodgkin’s lymphoma, systemic lupus erythematosus, and familial eosinophilia. Hyper reactive airway is important to be diagnosed early as this may result in perioperative respiratory dysfunction ranging from coughing, stridor to atelectasis. The results of our study show a mean absolute eosinophil count of 718 (p =0.0457) for five patients undergoing nephrectomy. However, there was no respiratory event encountered. The three variables of bronchospasm, stridor and decreased SPO2 levels serve as good parameters to check for complications that may arise out of high eosinophil count during general anesthesia

Keywords


perioperative absolute eosinophil count, hyperactive respiratory dysfunction, bronchospasm, inflammatory mediators, general anesthesia

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