A COMPARATIVE STUDY OF THYROID FUNCTIONS IN PREMENOPAUSAL AND POSTMENOPAUSAL WOMEN

Dr Chinmayee Sarma Bhargav, Dr Dipti Bania

Abstract


Introduction : Thyroid gland plays a vital role in regulating overall body metabolism including reproductive function.
Thyroid diseases are among most prevalent endocrine disorders worldwide especially in women, second only to
diabetes. Menopausal age is more prone to develop hypothyroidism. Hypothyroidism and menopause share some
symptoms. So it can be difficult to differentiate. So routine screening of serum TSH and Tri iodothyronin and Thyroxin
level in climacteric period is recommended. Taking this aim and objective this comparative cross sectional study of
thyroid function in pre and postmenopausal women was processed.
Objective : To evaluate and compare the serum TSH and thyroid hormone levels in pre and postmenopausal women and
to find out the effect of any postmenopausal hormonal changes on thyroid functions.
Method : 56 premenopausal women of age group 20 – 30 years and 56 postmenopausal women of age group 50 – 60
years are evaluated for serum TSH and T₃, T₄ level by ELFA technique on VIDAS instrument.
Statistical Analysis : Unpaired student's t test
Result : Mean serum TSH level in post menopausal women found higher than that in premenopausal women but
difference was not significant. Serum T₃ and T₄ level in postmenopausal women found slightly lower than in
premenopausal women.
Conclusion : Postmenopausal women should be monitored for serum TSH and thyroid hormone level for reducing risk
of thyroid dysfunction


Keywords


Premenopausal , postmenopausal women, serum TSH, Tri iodothyronin, Thyroxin

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