CORRELATION BETWEEN SERUM CA125 LEVELS AND OVARIAN CANCER: ROLE IN DIAGNOSIS AND STAGING.

Dr. Akhtar Un Nisa Salaria, Dr. Jagriti Singh, Dr Faiza Hafiz

Abstract


Introduction: This study intends to find correlation between CA125 (carbohydrate antigen 125) and diagnosis of
ovarian cancer and staging.
Methods: Patients with ovarian tumors signed out in the Department of pathology, between January 2017 and December
2018 were included. Serum levels of CA125 were noted. Ovarian tumors were staged according to FIGO staging system
.The correlation between CA125 levels and staging and histopathology were evaluated. Chi square analysis was done
and p value <0.05 was considered statistically significant.
Results: 50 ovarian cancer patients were included in the study period. The mean age was 48.5+/-10.1
years.Preoperative Ca125 level did not correlate significantly with the stage of ovarian cancer. Highest levels of CA 125
were found in serous tumors. Mean serum CA125 concentration in papillary serous adenocarcinoma patients was
1448+/-310 U/ml whereas in mucinous adenocarcinoma was 760+/- 120 U/ml.
Conclusion : In our study, preoperative CA125 levels correlated well with the ovarian cancer but did not correlate with
the FIGO staging


Full Text:

PDF

Refbacks

  • There are currently no refbacks.