'A STUDY ON CORRECTED QT INTERVAL AS VITAL MARKER IN CARDIAC COMPLICTIONS IN HYPOTHYROIDISM- CASE CONTROL STUDY''

Dr.Mohammed Rifaz, Dr. Balachadra S Bhat

Abstract


INTRODUCTION:Thyroid diseases are common conditions seen worldwide. According to projection from various studies, nearly 42 million people are suffering from various thyroid disorders. Among  the endocrine disorders, the most commonly encountered disease is hypothyroidism.Thyroid hormone plays an important role in regulating the cardiovascular system and causes electrophysiological changes in the heart’s conducting system. We have assessed whether Corrected QT serve as tool for knowing the status of cardiac functioning, its recovery and variations in hypothyroidism. Measuring QTc in hypothyroidism patients is a simple, inexpensive, and non-invasive method of measuring cardiac changes. It also serves an index of inhomogeneity of ventricular repolarization and heart rate. It can be assessed as a measure of cardiac autonomic modulation in patients with clinical hypothyroidism.

 

METHODS :A total of 128 participants were included in the study with 64 were hypothyroid patients and 64 healthy individuals. In the study, Corrected  calculated by Bazett’s formula from ECG and Statistical significance were compared between above two groups.

RESULTS :A total of 64 hypothyroid patient and 64 healthy individuals were studied . The average age of the hypothyroid group was 39.65 Years (SD+/-11.52) and Euthyroid group was 36.03Years (SD+/-7.59) .The average QTc interval for the study group was 0.436 S (SD+/-0.0517) and that of the control group was 0.402 S (SD+/- 0.030),This was statistically significant with P-value <0.001

CONCLUSION :Thus study will emphasize on clinical evaluation of hypothyroidism and value of electrocardiography in hypothyroid patients and clinicians to correlate the thyroxine effects with the ventricular functionality using Corrected QT as vital marker of cardiac assessment in Hypothyroid patient at the bedside.


Keywords


QTd- QT dispersion, QTc- QT corrected, ECG- Electrocadiogram

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