Dr Shaifali Patil, Dr Salomi Singh, Dr Shivali Tripathi


BACKGROUND: The study aims at comparing the low dose of vaginal misoprostol and dinoprostone gel for the induction of labor.

METHODS: The study was conducted on 200 pregnancy females, randomized into two groups, each group having 100 women. First group received misoprostol per vaginally and second group received dinoprostone gel. The time interval from induction to delivery, mode of delivery, labor and fetal complications were recorded.

RESULTS: The induction to delivery interval was significantly less in misoprostol group as compared to dinoprostone group (14.21 vs 16.35 hours; p<0.01). Therefore, early labor and early delivery is seen with misoprostol as compared to dinoprostone.

CONCLUSIONS: As shown in this study, the time intervals from induction to delivery interval were significantly shorter and the requirement of oxytocin was less for augmentation of the labor with misoprostol than dinoprostone gel with no difference in maternal and neonatal complication rate.


Dinoprostone gel, Labor induction, Misoprostol, Labor Analgesia,

Full Text:



Houghton Mifflin Company. Induction of Labor. In: American Heritage Dictionary, eds The American Heritage Dictionary, 4th ed, Boston, MA. Houghton Mifflin Harcourt; 2006:1074.

Shibira MV. One-year randomized trial comparing oral v/s vaginal misoprostol tablets for induction of labor in term pregnancies. J Obstet Gynaecol 2006; 25:1-106

Witter FR. Prostaglandin E2 preparation for preinduction cervical ripening. Clin Obstet Gynecol. 2000; 43:469-74

Li XM, Wan J, Xu CF, Zhang Y, Fang L, Shi ZJ, Li K. Misoprostol in labor induction in term pregnancy: a meta-analysis. Chin Med J(Engl). 2004; 117:449-52

Schroder AK, Taulhert S, Diedrich K. Induction of labor at term with misoprostol: an effective safe and inexpensive alternative. Zenrealbl Gynecol. 2004; 126:54-8.

Neiger R Greaves PC. Comparison between vaginal misoprostol and cervical dinoprostone for cervical ripening and labor induction. Tennessee medicine: journal of the Tennessee Medical Association. 2001 Jan;94(1):25-7.

Patil KP, Swamy MK, Rao KK. Oral misoprostol vs intracervical dinoprostone for cervical ripening and labor induction. J obstet Gynec India. 2005;55(2):128-31.

Alaparthi PN, Aravinda K. Comparative study of induction of labour with intravaginal misoprostol and intracervical dinoprostone gel. JOURNAL OF EVOLUTION OF MEDICAL AND DENTAL SCIENCES-JEMDS. 2016 Mar 14;5(21):1120-3

Patil P, Patil A. Misoprostol v/s cerviprime gel for induction of labor. International journal of medical research and review. 2013 Jun 30;1(02).


  • There are currently no refbacks.