Dr Gaurav Gupta, Dr Shivanshu Misra


Autosomal-dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disease. It is characterized by multiple cysts of variable size diffusely scattered throughout the renal cortex and medulla [1]. It is a systemic disorder leading to chronic renal failure and hypertension. Autosomal dominant polycystic kidney disease (ADPKD) is an inherited disorder associated with multiple cyst formation in the different organs. Extrarenal cysts are mainly found in liver, but may involve pancreas, spleen and brain but with lesser frequency. Affected individuals have a relatively high rate of cardiac valvular abnormalities, especially mitral valve prolapse, as well as intracranial, aortic or coronary aneurysms, abdominal and inguinal hernias and colonic diverticulosis [1]

We report a case with both pancreas divisum and cholelithiasis in patient of ADPKD.A 34-year-old gentleman with ADPKD presented with pain upper abdomen associated with vomiting and fever. Imaging studies revealed multiple renal and hepatic cysts, cholelithiasis, pancreatitis and acute fluid collection.Pancreatitis is common cause of abdominal pain in patients with ADPKD. Pancreas divisum may be a predisposing factor for acute pancreatitis in ADPKD.


Autosomal dominant polycystic kidney disease (ADPKD), Extrarenal cysts, Pancreas divisum

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