THE STUDY OF ANTIMICROBIAL SENSITIVITY PATTERN OF COAGULASE-NEGATIVE STAPHYLOCOCCI (CONS) ISOLATED FROM DIFFERENT CLINICAL SPECIMENS IN TMMCH, MORADABAD, UP.

Raees Ahmed, Sudhir Singh, Anita E. chand

Abstract


Background: In now days Coagulase negative staphylococci (CoNS) have been reported as a major public health problem worldwide. Low percentage in the antimicrobial susceptibility against CoNS has become a growing problem in developing countries.

Objective: To determine the incidence and antimicrobial sensitivity pattern of coagulase negative staphylococci.

Material and Methods: All the isolates were identified as per standard protocols and antimicrobial sensitivity pattern was determined by Kirby-Bauer disc diffusion method as par  CLSI (Clinical and Laboratory Standards Institute) guidelines.

Results: A total of 53 (13.25%) coagulase-negative Staphylococci (CoNS) isolated among 400 Staphylococcal isolates.  CoNS shows maximun sensitivity against Vancomycin (100) and minimum susceptibility against Penicillin-G (0%).

Conclusion:  It is concluded that to preserve the value of vancomycin for the treatment of life threatening CoNS infections in future, there is need of regular surveillance of methicillin resistance among CoNS to avoid the use of powerful antibiotics for initial infections. 


Keywords


CoNS, Nosocomial infection, Vancomycin

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