Dr. Srirupa Tejasvi Kalagara, Dr. P. Manimekalai


Introduction: Thrombocytopenia literally means decreased platelet count. It is defined as a platelet count <1,50,000/μL. Platelets play a major role in hemostasis and it is essential to find the cause of thrombocytopenia and correct it.


Aims & Objectives: To elucidate the causes of thrombocytopenia and their incidence and to study the clinical profile and laboratory parameters in patients with thrombocytopenia. Materials and Methods: A total of 200 patients with thrombocytopenia admitted to Sree Balaji Medical College and Hospital were evaluated. Patients with platelet count <1.5 lakh/mm3 were included in study whereas patients with malignancy thrombocytopenia due to chemotherapy were excluded.

Results: The present study includes patients between 18-70 years of age. The highest incidence of thrombocytopenia was seen in the age group 21-30 years (30%) followed by 18-20 years (24%) and 31-40 years (22%). Diseases causing thrombocytopenia such as megaloblastic anemia and infections (malaria, dengue, enteric fever, and septicemia) were found to be common in the younger population. In our study, the majority of the patients were younger than 40 years.

Conclusion: Major cause of thrombocytopenia was found to be due to dengue fever. Bleeding manifestations were noted in one-third of the population.


Thrombocytopenia, Platelet count, Bleeding manifestations, causes of thrombocytopenia, dengue fever.

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